125 Li Ka Shing Center

Coleen Murphy, Princeton University

Dr. Noah Zaitlen, Assistant Professor, UCLA Abstract: Positive genetic correlation estimates are commonly interpreted as evidencethat two traits share overlapping biological features. With the increasing avail-ability of large consortium and biobank datasets, considerable research activityhas focused on cataloging the genetic correlation structure of complex humantraits in order to better understand shared etiology and transdiagnostic riskfactors.…

Sean Eddy, Professor, Harvard University Abstract: Computational recognition of distant sequence homology is a key to studying ancient events in molecular evolution. The better our sequence analysis methods are, the deeper in evolutionary time we can see. A major aim in the field is to improve the resolution of homology recognition methods by building increasingly…