Bioengineering Seminar Spring 2022: Physicochemical properties of extracellular matrix: Key to function, Clue to mechanism

Zoom (registration link below)

Shyni Varghese, Professor of Biomedical Engineering, Mechanical Engineering & Materials Science, and Orthopaedic Surgery, Duke University Abstract: Reciprocal interactions between cells and their microenvironment are fundamental to multiple cellular processes necessary for tissue development, homeostasis, and regeneration. In this talk, I will discuss our efforts to delineate the role of the extracellular matrix on cellular…

Short Range Order and the Evolution of Deformation Mechanisms in Both High and Low Entropy Alloys: Nano Seminar series

4 LeConte Hall

Prof. Andrew M. Minor, UC Berkeley, Materials Science & Engineering This talk will describe our recent results utilizing energy filtered diffraction, 4D-STEM and in situ TEM nanomechanical testing that provide insight into multiscale deformation phenomena in α-titanium and the CrCoNi medium entropy alloy. Using energy-filtered TEM and HRSTEM techniques it is possible to directly image,…

The great nuclear escape: the mechanism of membrane deformation during non-canonical nuclear export in herpesviruses

106 Stanley Hall

Katya Heldwein, Tufts University School of Medicine Herpesviruses are large viruses that infect nearly all vertebrates and some invertebrates and cause lifelong infections in most of the world’s population. During replication, they export their capsids from the nucleus into the cytoplasm by an unusual mechanism termed nuclear egress. Too large to fit through nuclear pores,…