Unraveling the role of isonitriles for potential TB therapeutics

From isonitriles to biofilms to potential anti-TB drug targets! UC Berkeley scientists from the Zhang lab are exploring the mechanism and role of the isonitrile-forming enzyme, Rv0097, with relation to virulence in Mycobacterium tuberculosis. Graduate student Antonio Del Rio Flores discusses ongoing work with Rv0097.

Illuminating gene silencing with an electron beam

A new study in Science shows how electron cryo-microscopy (cryo-EM) can shed light on the molecular details behind the gene silencing mechanisms that power cell differentiation.