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The UC Berkeley Proteomics/Mass Spectrometry Laboratory (P/MSL) was founded in 2004 as part of UC Berkeley’s Cancer Research Laboratory. In 2007, we became the Vincent J. Coates Proteomics Laboratory, affiliated with QB3, in order to provide improved access to proteomics services.

We are located in Stanley Hall with a “wet” biochemistry area for protein sample preparation and an array of mass spectrometers. The P/MSL provides proteomics services principally through mass spectrometry. Currently we have two Thermo LTQ XL linear ion trap mass spectrometers and a Thermo Fusion Lumos mass spectrometer.

We specialize in the identification of proteins from complex samples using “bottom up” proteomic approaches and multidimensional chromatography (MudPIT). We can locate post-translational modifications, often even on complex samples. We also offer high-resolution analysis for isobaric (TMT),  SILAC or label free (LFQ) relative quantitation. Many other types of analysis are possible including “top down” proteomics. Please check our services offered, listed in the P/MSL navigation menu, to see details about analyses we routinely perform and inquire about services not listed.

If you are looking for small molecule mass spectrometry, visit the webpage of our friends in the QB3/Chemistry Mass Spectrometry Facility.

Lab equipment at the Vincent J. Coates Proteomics/Mass Spectrometry Laboratory Core Facility.
An Orbitrap Fusion Lumos at the Vincent J. Coates Proteomics/Mass Spectrometry Laboratory Core Facility at UC Berkeley, RRID:SCR_025852.

Contact

Rob Maxwell, PhD
Facility Director

B205 Stanley Hall, UC Berkeley
robmaxwell@berkeley.edu
510-666-3619

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