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QB3 Genomics Rates (Effective for work completed after June 1, 2026)

Illumina By-the-Sample

(Prep + 150PE Illumina Data) Reads Data UC Affiliate External Pricing unit
DNAseq (regular insert size) 8-10 Gbp $150 $165 $175 Per sample
RNAseq (poly-A selection) 20-25 M Pairs $205 $225.50 $236 Per sample
RNAseq (w ribodepletion) 20-25 M Pairs $340 $374 $391 Per sample
Human Exome (100x) 5 Gbp $220 $242 $253 Per sample
Extra Data/Sequencing Only  (repooling not included)* 8-10 Gbp $30 $33 $35 Per sample
Illumina Resequencing*  (pooling included) 8-10Gbp $50 $55 $57.50 Per sample
*Only available for libraries constructed with FGL/GSL indexes, high base diversity, and within 300-600bp fragment size free of adapter dimer

Illumina Library Prep Only

UC Affliate External Pricing unit
DNA $100 $110 $115 Per sample
mRNA, oligo-d(T) $150 $165 $173 Per sample
RNAseq, Ribodepletion* $300 $330 $345 Per sample
Low Input, including FFPE (Add-on) $50 $55 $60 Per sample
*Human/Mouse/Rat – contact us for custom ribodepletion

10X Preps

UC Affliate External Pricing unit
10x single cell chip $440 $484 $506 Per sample
10x 3′ library gel bead kit v2 $2000 $2,200 $2300 Per sample

PacBio

Reads Data UC Affiliate External
HMW Extraction (PCI manual) Cost varies by sample type can be more or less than listed 1000 1100 1150
HiFi (WGS/Metagenomics/Microbes, etc) $420 $462 $485
IsoSeq Lib Prep (Total RNA to cDNA only) $240 $264 $276
Kinnex Array Prep (BulkRNA/16s) $1015 $116.50 $1168
Amplicon Lib Prep $155 $170.5 $180
Revio SMRTcell (SPRQ Chemistry) 5-10M (varies by application)  60-120Gb (varies by application/sample) $1500 $1650 $1725
Revio NX SMRTcell 15-30M (varies by application) 180 – 360Gb (varies by app/sample) $2100 $2310 $2415
Revio NX SMRTcell – Per Use 5-10M (varies by application)

(no <5kb molecules)

 60-120Gb (varies by application/sample) $700 $770 $805

ONT

Please inquire for Oxford Nanopore Sequencing. At this time we do not have the bandwidth for library preparations but have a self-service P2 Solo instrument available for use after a training or core staff are available to load and sequence user prepared libraries.

iTag/Amplicon Sequencing

We are no longer able to offer amplicon services at the facility but highly recommend our colleagues at Rush University. Please reach out to Kevin and Stefan and they can assist you as they have many of our former users with gold star reviews.

All MiSeq and NextSeq Run Types can be customized based on the cycles in the kit as they are single lane runs. Read 1 must always be 25 cycles minimum and no read can surpass 300 cycles.

Illumina Sequencing MiSeq

Reads Data UC Affiliate External Pricing unit
MiSeq i100 300cycle 300SR/150PE 5M 1.5Gbp $600 $660 $690 Per lane
MiSeq i100 600cycle (300PE) 5M 9Gbp $830 $913 $952 Per lane
MiSeq i100 100cycle (100SR) 25M 5Gbp $760 $836 $874 Per lane
MiSeq i100 300cycle (150PE/300SR) 25M 15Gbp $1150 $1265 $1322.50 Per lane
MiSeq i100 600cycle (300PE) 25M 30 Gbp $1,500 $1,650 $1,725 Per lane
MiSeq i100 1000cycle (500PE) 25M ??? 50 Gbp ??? $2040 $2244 $2346 Per lane

NextSeq2000 (All XLeap Chemistry)

Reads Data UC Affliate External Pricing unit
NextSeq 2000 P1 100 Cycle (100SR/10x)** 100 M 10 Gbp $1,200 $1,320 $1,380 Per lane
NextSeq 2000 P1 300 Cycle (150PE)** 100 M RP 30 Gbp $1,300 $1,430 $1,495 Per lane
NextSeq 2000 P1 600 Cycle (300PE)** 100 M RP 60 Gbp $2,010 $2,211 $2,311.50 Per lane
NextSeq 2000 P2 100 Cycle (100SR/10x) 400 M 40 Gbp $1,400 $1,540 $1,610 Per lane
NextSeq 2000 P2 200 Cycle (100PE) 400 M RP 80 Gbp $2360 $2,596 $2,714 Per lane
NextSeq 2000 P2 300 Cycle (150PE) 400 M RP 120 Gbp $3360 $3696 $3,864 Per lane
NextSeq 2000 P2 600 Cycle (300PE) ** 400 M RP 180 Gbp $3,730 $4,103 $4,289.50 Per lane
NextSeq 2000 P3 100 Cycle (100SR/10x)** 1.2 B 120 Gbp $2,840 $3,124 $3,266 Per lane
NextSeq 2000 P4 50 Cycle*  1.8 B  90 Gbp $1350 $1485 $1552.50 Per lane
NextSeq 2000 P3 100 Cycle (100SR/10x) 1.8 B 180Gbp $3115 $3426.50 $3582.25 Per lane
NextSeq 2000 Custom Read/Index Primer* *only charge once per lane $350 $385 $403 Per lane
**Rates in flux, ideally will go down, *promotional rate

NovaSeq X (lanes)

Reads Billion Data GB UC Affliate External Pricing unit
NovaSeq X 10B 10X 1.25 125 $1,205 $1,325.50 $1,385 Per lane
NovaSeq X 10B 100SR (6-8 week) 1.25 125 $1,205 $1,325.50 $1,385 Per lane
NovaSeq X 10B 150PE 1.25  RP 375 $1,535 $1,688 $1,765 Per lane
NovaSeq X 25B 10X only 3.2 375 $1,565 $1,721.50 $1800 Per lane
NovaSeq X 25B 150PE 3.2  RP 875 $2,600 $2,860 $2,990 Per lane
Turnaround Time on ready to sequence (already pooled) 150PE 10B and 25B lanes is 5-7 days post QC passing. Specs for Novaseq listed are conservative, generally data returns are 25-30% higher.
UCB does not have a NovaSeq X, all lanes are sent to external providers in industry and academia based on cost and turnaround. We comply with all government policies. We will happily tell you where your samples are being sequenced but we cannot list our industry collaborators here due to campus brand and advertising rules. Academic sequencing is performed at the UCSF CAT Lab. All sequencing will transtion to the CAT lab soon.

QC Services

Quantification

UC Affliate External Pricing unit
Qubit $7 $7.7 $8 Per sample
qPCR $23 $25.30 $26 Per sample

Fragment Analysis

UC(Prep/QC only)* Affliate External Pricing unit
Fragment Analyzer $10/$25 $11/$26.40 $17/$28 Per sample
Bioanalyzer (rec. for RNA) $21/$49 $23.10/$53.90 $24/$56 Per sample
Femto Pulse (HMW) $29/$41 $31/$45.10 $33/$47 Per sample
*The rates are lower when requested prior to any lib prep.  QC only rates are more expensive due to time spent billing, finalizing more thorough reports, and sending correspondence emails.

Purification

UC Affliate External Pricing unit
Bead Clean $38 $41.80 $44 Per sample
Pippin Size Selection $172 $189.20 $198 Per sample

Custom Services

UC Affliate External Pricing unit
Hourly Cost $100 $110 $115 Per hour
*Custom services are billed as Labor, Disposables, and Machine use where required

CGRL

UC Affliate Pricing unit
Up to 5 users $545 $818 Per 2 months
Additional User $110 $165 Per 2 months

Rates are subject to change throughout the year but as per UC policy change annually on July 1. Submissions will be impacted by the rates in the submission system at the time your samples are received not at the time your submission is generated. 

Internal Rates apply to any project paid with a UC fund code. It has nothing to do with user affiliation and everything to do with the project fund code. Affiliate rates are extended to researchers at LBNL & LLNL, the JGI, CHORI, Mills College, and Co-funded collaborators of UCB PIs (with written confirmation from the UCB PI).

External rates apply to all other groups (non-profit and for-profit). We do not charge sales tax.

If you are ready to submit your samples, with all sample information in hand, proceed to our online submission portal. UC researchers should email cgrl@berkeley.edu to get a submission account as you cannot setup an account on your own as we need to allow you to designate your lab and campus affiliations.

Quotes & POs

External user quotes will be honored for the terms dictated on the quote provided the samples are received within the terms of the quote (generally 60 days, but always expiring on 7/1 of the issuing year). External quotes should be requested to generate POs for billing accounts before generating a submission in our system; however, POs are set-up by your home institute, we do not require any contract or PO in place to work with any entity but it is the user’s responsibility to know the rules within your own institute. If you request work you will be billed and expected to pay whether you followed the rules at your institute or not. For large requests, we may hold work until a PO is received. It is always best practice to get a PO and then send samples.

You may generate a cost estimate WITHOUT a submission portal account with this link.

Cost Estimation and PO generator

The table at the end will provide an estimate of cost based on your rate level (explained below). If you would like an official quote to get a PO after using the tool, email Shana McDevitt your Quote Only M# and she will review the quote and provide a signed PDF. Note that any service that sums to $0 is not valid and indicates a service that is likely custom and/or needs to be reviewed with the facility before it can be priced. If in calculating your project your table results in a service sum on $0, please reach out so that a proper consultation can be done. There a very few limitations in what we can offer but sometimes a conversation is easier than a complex Q&A software portal.

If you have a submission system account you can also login and generate a “Quote Only” submission that will generate a PDF. All quote only submissions with or without an account can be converted into submissions later when samples are ready.

You may obtain UC Berkeley’s current W-9 from the Controller’s Office webpage.

Please contact our Financial Analyst to get bank or DUNS information.

If you have any questions regarding these rates, please contact Shana McDevitt.

 

Business Contracts

The fastest way by far to set up a contract is through UC Berkeley’s Research Infrastructure Commons. If our template contract is acceptable, it can be approved and signed within a couple weeks. (we are working on a Docusign version now, it’s still in the approval queue as of 7/5/24)

Other contracts can take 4-6 months to be approved by the UC contracts office, so please start the contract conversation immediately if you require a contract to work with us. It is VERY unlikely that UCB will sign a contract initiated by another institution. We cannot sign NDAs or MTAs on behalf of UCB.

Please contact Shana McDevitt for all contractual matters.

Invoicing Timeline

Pre-billing is not allowed for any work. Do not ask for any amount, for any reasonBilling is performed once a month at the end of the month generally around the 7th, and invoices are (generally) sent the third week of the month following billing but you can request an out of cycle invoice if the work is complete. Please review your LIMs submission status for “Ready to Invoice” of “Work Complete” status.  If your funds are expiring and you need urgent billing please let us know before you submit your work. If you cannot allow 2 months for invoicing and payment do not submit without approval from the Operations Director.